NICE emphasises that pharmacological interventions should complement, not replace, lifestyle modifications that form the foundation of treatment for both obesity and dyslipidaemia
Table 1)
So GLP-1 exerts broad benefits like suppressing appetite, delaying gastric emptying, decreasing glucose production as well as lowering the risk of cardiovascular diseases [3][5]
Most common: nausea (38-43%), diarrhea (33-35%), vomiting (20-21%), constipation (22-25%), decreased appetite (18-19%)
Age-related Atrophy of the Stomach Lining : As people age, the stomach lining may atrophy, leading to reduced production of hydrochloric acid and intrinsic factors, which are necessary for the absorption of vitamin B12
Staying well hydrated and keeping up a healthy fibre intake can help